A documented two-PDE5 mint with unverified current plan pricing. Research on sildenafil/tadalafil does not test this different pair.

This mint combines tadalafil and vardenafil. It is a distinct prescription from the sildenafil/tadalafil/B12 chew and from a vardenafil-only mint. Treating every two-drug ED product as equivalent hides a material formula change.

Changing one ingredient changes the evidence

The formulation combines persistent tadalafil exposure with vardenafil-specific considerations, including rhythm history. The intended benefit and monitoring need explanation from the prescriber rather than inference from a combination label.

The documented product is a tadalafil/vardenafil mint described in Hims safety information. The listed delivery format is compounded combination mint. FDA does not approve compounded finished products or verify their safety, effectiveness and quality before marketing. A licensed prescriber and pharmacy do not turn the compound into an FDA-approved product. FDA: Compounding and the FDA — questions and answers

Product
Hims Tadalafil + Vardenafil Hard Mints
Provider
Hims
Listed ingredients
Tadalafil + vardenafil
Format
Compounded combination mint

What the advertised price actually buys

A current selectable plan and matching price were not verified. The public safety document is useful for ingredient identification but cannot supply the missing invoice details.

Keep four numbers together: the amount due now, the quantity supplied, the period covered and the next renewal total. A monthly equivalent can make a prepaid plan look like a monthly bill. A low unit price can require a larger purchase. Neither figure tells you how often a medicine should be taken; only the prescription supplies those directions.

Public documentation
Hard Mints formulation safety library
Current price
Not verified for a matching selectable plan
Not 3-in-1 Hard Mints
Different PDE5 pair from sildenafil/tadalafil/B12
Additional assessment
Vardenafil makes rhythm-history review relevant

What is supported—and what remains open

The often-cited daily tadalafil plus as-needed sildenafil study did not use vardenafil. It therefore cannot establish the efficacy, timing or safety of this mint. We did not verify a controlled trial of the finished preparation.

The evidence basis identified for this review is individual-drug information; sildenafil/tadalafil studies do not test this pair. The remaining uncertainty concerns finished-product comparative evidence and account availability. This distinction matters because a study can differ in strength, route, schedule, patient group or the outcome measured. A favorable result for one ingredient or regimen is not a clinical result for every product that shares its name.

Our review uses product and policy documents for commercial facts, and labels, government information and primary research for the medical context. We did not purchase or personally test this treatment, measure response times, or audit the provider’s clinical decisions. A missing matched study in this review is an evidence limit, not proof that a product never helps anyone.

The safety discussion this formula needs

PDE5 medicines can cause a dangerous blood-pressure drop with nitrates or nitrites, including recreational “poppers,” and must not be combined with riociguat. Tell the prescriber about all medicines, supplements, blood-pressure problems and heart conditions. Do not add another ED medicine or increase an amount based on an advertisement or this review. MedlinePlus: Sildenafil MedlinePlus: Tadalafil

Headache, flushing, indigestion, congestion and dizziness are among the adverse effects described for these medicines. The exact risk depends on the drug, prescription and medical history. A short list here cannot replace the complete pharmacy information or an individual assessment.

Overlapping ED medicines
The tadalafil label advises against use with other PDE5 inhibitors because combination safety and efficacy have not been established in labeling. A prescribed compound does not remove that uncertainty. DailyMed: Tadalafil prescribing information, including section 5.11
Rhythm history
Tell the prescriber about prolonged QT, relevant family history and rhythm medicines. This ingredient has specific precautions beyond a generic ED checklist. MedlinePlus: Vardenafil

What the public listing does not settle

Hims Tadalafil + Vardenafil Hard Mints is classified here as “confirm current offer.” Documented in the safety library; current sale availability unverified. A page being online does not verify shipping to every state, current stock, eligibility, or the formula that will be dispensed to a particular patient.

Ask why this specific pair was selected and whether an account offer still uses the exact formulation described in the safety library.

Verify before ordering
Exact product name; complete ingredients and strengths; dispensing pharmacy; state access; clinician approval
Practical distinction
A safety document can describe an older formulation without confirming a current new-customer offer.

Refills, changes and cancellation

Hims support asks for cancellation at least 48 hours before the next order. Its billing guidance distinguishes the charge and processing date from the delivery date; the first refill may be scheduled sooner than a reader expects from a simple month count. Ending the subscription does not reverse an order that is already processing or shipped, and a refund after pharmacy processing is not guaranteed. If a clinician changes the medicine, separately confirm that the old pharmacy order and the next account charge were updated.

A customer-service action changes an account; a prescribing decision changes treatment. Keep both confirmations when changing plans. If symptoms or adverse effects require attention, contact the clinical team rather than waiting for the next scheduled billing event. Hims Support: canceling a subscription · Hims Support: refund policy · Hims Support: when billing occurs · Hims Support: changing the next order date

Compare the products that differ in a meaningful way

A useful next comparison for Hims Tadalafil + Vardenafil Hard Mints changes one identifiable feature: the ingredient combination, the dosage form, the schedule or the provider’s commercial terms. The related reviews below make those differences visible. They are not a clinical ranking or a recommendation to substitute medicines.

Use the comparison desk to place up to three fact sheets together. The plan-cost guide explains why comparing a monthly equivalent with a per-dose headline can produce the wrong conclusion.

Questions to take to the consultation

What evidence and monitoring support this specific two-drug combination?

Also ask what would count as a useful response, what side effects should prompt contact, who reviews an unsatisfactory result, and how a change reaches the pharmacy before the next order. Keep the answer tied to this exact prescription, not the provider’s product family.

Prescription question
Why this ingredient list, strength, route and schedule for the symptoms discussed?
Payment question
What is charged today, what renews, and when does cancellation need to be recorded?
Follow-up question
How do I reach a clinician, and what should be handled through urgent or emergency care?

When account support is not enough

Seek emergency care for an erection lasting more than four hours or chest pain. Tell the treating team which medicines were taken and when. Sudden loss of vision or hearing needs prompt medical attention; do not wait for a routine subscription-support reply. MedlinePlus: Sildenafil MedlinePlus: Tadalafil

Read the underlying material

Sources & evidence notes

Provider documents support product and commercial details. Clinical references have their own study or labeling limits. Accessed October 7, 2026; indexed abstracts were used for the listed studies.

  1. Hims: Hard Mints formulation safety library

    Provider formulation document; includes options not confirmed in the main catalog

  2. Hims: current ED treatment catalog

    Provider catalog; individual named offers and starting prices

  3. MedlinePlus: Vardenafil

    Government patient drug information; standard products, not compounded equivalents

  4. Hims Support: canceling a subscription

    Provider policy; 48-hour notice and orders already processing

  5. Hims Support: refund policy

    Provider policy; no guaranteed refund after pharmacy processing

  6. Hims Support: when billing occurs

    Provider policy; next order date, charge timing, and subscription intervals

  7. Hims Support: changing the next order date

    Provider support; refill rescheduling differs from cancellation

  8. Cui et al. (2015): daily tadalafil with as-needed sildenafil

    Primary clinical study; 180 patients, specific regimen, abstract reviewed via NCBI

  9. DailyMed: Tadalafil prescribing information, including section 5.11

    Prescribing label; not evidence for the 4Play combination

  10. FDA: Compounding and the FDA — questions and answers

    Government guidance on compounded medications

  11. MedlinePlus: Sildenafil

    Drug information; standard sildenafil products

  12. MedlinePlus: Tadalafil

    Drug information; standard tadalafil products